The influence of proteinic fraction on electrophoresis and concomitant quantitative measurement of immunoglobulins in patients with Multiple Sclerosis
The influence of proteinic fraction on electrophoresis and concomitant quantitative measurement of immunoglobulins in patients with Multiple Sclerosis
The influence of proteinic fraction on electrophoresis and concomitant quantitative measurement of immunoglobulins in patients with Multiple Sclerosis
DROSSO TH,KOUNTOURIS D, KOSSIONI E,LIAPIS A, SIMA A AND SPAKOURIS D.
Internal Medicine and Microbiology, Pammakaristos Hospital Iacovaton 43 Athens 11144
Medical Neurological Center, Athens, Greece.
This study tries to test an observation with multiple sclerosis (MS) in electrophoresis of proteins and evaluates if this influence contributes in disease diagnosis. A quantitative measurement of immmunoglobulins IgA, IgG, and IgM was concomitantly performed. Eighty-six patients with known MS aged 17-56 participated in this study. Proteinic electrophoresis was performed on acetic cellulin Helena and the quantitative assay of Iga, IgG and IgM with Turbi Tissue System-Behring.
Table 1.
Variable
Mean
Minimum
Maximum
s.d
Normal limits
Albumin
54.41
46
62
3.93
52.3-66
a1
3.155
2.2
4.5
0.43
3.3-7
a2
11.527
0.3
16.3
1.77
6.3-11.7
β
14.167
7.8
19.9
2.22
7.8-14.3
γ
16.176
9.4
30.2
3.18
11.1-20.4
IgA
1061.2
650
1940
215.54
80-01700
IgG
209.19
60.9
463
88.57
85-450
IgM
179.72
19
874
132.52
60-370
A decrease in a1 globulin was observed. We have some clinical evidence that patients with MS with a low a1 globulin have a grave clinical picture. This observation has to be further tested. There is no influence on quantitative immunoglobulins `assay.
Abstract published in EUROPEAN JOURNAL ON NEUROLOGY 1996;3(5)paper presented at the 2nd Congress of the European Federation of Neurological Societies, Rome, Italy, 30 October -3 November 1996.
Το οπτικό νεύρο αναμενόμενα οποιαδήποτε βλάβη και αν έχει εξαιτίας οποιασδήποτε αιτίας ή ανατομικής διαταραχής, θα έχει μια μείωση της όρασης, η οποία θα εκδηλώνεται με μια εικόνα τύφλωσης Περισσότερα...
Αυτό που κυρίως αντιλαμβανόμαστε οι περισσότεροι, δυστυχώς επίσης και οι γιατροί, είναι ότι το στερητικό σύνδρομο είναι κυρίως έκφραση μιας τοξικομανούς αιτίας Περισσότερα...
Παρακολουθούν τώρα*
ΑΥΧΕΝΙΚΟ ΣΥΝΔΡΟΜΟ - ΜΕΡΟΣ 3 - 19/02/2011
*Ο Δρ. Δημήτρης Κουντούρης έχει συμμετάσχει σε πολλές τηλεοπτικές εκπομπές σαν ειδικός επιστημονικός σύμβουλος επί θεμάτων Νευρολογίας και Ψυχιατρικής. Για πλήρη λίστα των τηλεοπτικών εκπομπών μπορείτε να επισκεφτείτε και το κανάλι μας στο YouTube: Neurology Channel
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