Όταν υπάρχει ένα εγκεφαλικό τραύμα ποικίλης αιτιολογίας και δε γίνεται αντιληπτό από τον ασθενή, ιδιαίτερα όταν αυτός είναι προχωρημένης ηλικίας, το σημαντικό είναι να δούμε αν υπάρχουν αιμορραγίες ή αιματώματα στον εγκέφαλο.
Το πλέον χαρακτηριστικό στοιχείο μιας προοδευτικής πολυεστιακής λευκοεγκεφαλοπάθειας είναι η σχεδόν ταυτόχρονη διαταραχή γνωστικών και κινητικών ικανοτήτων
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